The digital transformation of manufacturing industry can promote the development of green transformation and promote the differentiation of workers’ skill structure; On the other hand, it will also hinder the green development due to the huge energy consumption generated by the application of digital technology and facilities. In addition, the green transformation of manufacturing industry will also have differentiated impacts on the employment of labour with different skills due to the innovation of green technology. The existing research has not discussed too much about the interaction among the digital transformation and green transformation in manufacturing industry and labour structure. So, this paper uses the PVAR model to examine the dynamic relationship between digital and green transformation within the industrial sector from the perspective of labour structure, specifically analyzing the impact difference across regions. The results suggest that there is a reciprocal connection between the digitization of manufacturing sector and the labour structure, particularly in the eastern region of China, but the overall interaction between the two remains weak. The interactive between the green transformation of manufacturing industry and the labour structure in the central and western areas has been delayed over periods 1-6. Digital and green manufacturing transformation reinforce each other in central and western regions. However, the digital revolution in the manufacturing industry is hindered by the green transformation in eastern region.

Entrepreneurs are important actors in economic activities and creators of social wealth. Excellent entrepreneurs contribute their wisdom to the accumulation of social wealth and the promotion of high-quality economic and social development. The business environment is the main manifestation of the soft power of cities and regional economic development, and a better business environment can effectively attract enterprises and promote their sustainable growth. Using data from Chinese A-share listed companies from 2009-2019 as a research sample, the following research conclusions were drawn: (1) A better business environment helps enhance entrepreneurship. (2) A better business environment promotes entrepreneurship by reducing rent-seeking expenses and corporate credit costs. (3) Compared to traditional enterprises, high-tech enterprises are better able to enjoy the benefits brought by business environment optimization and further enhance entrepreneurship. When competition is low, entrepreneurs face lower rent-seeking expenses, which is conducive to stimulating entrepreneurship. The businessenvironment can promote fairness and bring more equal financing opportunities for enterprises, which has a higher impact on entrepreneurship for the group facing higher financing constraints. This study meticulously analyzes the impact ofthebusiness environment on entrepreneurship, providing references for the next steps of optimizing the business environment and enhancing entrepreneurship.

In the statistical standard of population aging adopted by the United Nations in 1956, the UN only focused on age, which is no longer a good statistical indicator in the context of deepening global population aging. To some extent, population aging is also the embodiment of social progress. This paper suggests improving the existing statistical standards of population aging to better adapt to the reality of social development.

Major economic and financial contractions usually go hand-in-hand with muted inflation. This has been true for the Great Depression, the Global Financial Crisis, as well as the Covid-19 crisis. In this paper, we theoretically highlight and discuss the evolution of instruments and approaches monetary-policy decision makers at the Federal Reserve have in lifting inflation to desired levels in times of the zero-lower bound, paying particular focus on more rigorous developments like asymmetric average inflation and temporary price-level targeting.

Cell-penetrating peptides (CPPs) have emerged as a promising strategy for enhancing the membrane permeability of bioactive molecules, particularly in the treatment of central nervous system diseases. CPPs possess the ability to deliver a diverse array of bioactive molecules into cells using either covalent or non-covalent approaches, with a preference for non-covalent methods to preserve the biological activity of the transported molecules. By effectively traversing various physiological barriers, CPPs have exhibited significant potential in preclinical and clinical drug development. The discovery of CPPs represents a valuable solution to the challenge of limited membrane permeability of bioactive molecules and will continue to exert a crucial influence on the field of biomedical science.

Cancer is the leading cause of death in the world, throughout the global researches of cancer treatment, people have a deeper understanding of cancer, and the treatment methods are constantly breakthrough. Conventional surgery, chemotherapy and radiotherapy have serious adverse effects and patients' quality of life is not significantly improved. Now, photodynamic therapy, photothermal therapy andthermodynamic therapy based on nanotechnology and materials technology are booming, and the development of these novel cancer therapies and their combination therapies brings more possibilities for cancer treatment. This review summarizes the research progress of novel cancer therapies based on nano and material technology from the aspects of mechanism of action and therapeutic methods, hoping to provide reference for their clinical application.

Since 2011, the conflict in Syria left the country with a devastating energy sector and fragile economy. The residents struggle daily to live with only two hours a day of electricity. The crisis encouraged some Syrians to assemble photovoltaic (PV) panels to generate energy. Unfortunately, the geopolitical risks, the inflation, and displacement are making the situation worse. The geopolitical risks are complex and multifaceted due to the ongoing war and the involvement of various regional and international actors. In this letter, we focus on the situation in war-torn Syria, its economy, and the opportunities for renewable energy development in the country. We also give some recommendations for academics and policy makers.

Noninvasive acquisition of deep tissue temperature has important applications in home health monitoring, hyperthermia safety control, and other domains. In this work, we present here a novel magnetically mediated thermoacoustic temperature measurement method. Utilizing coil to stimulate amplitude modulated magnetic field and ultrasound transducer to receive the generated thermoacoustic wave from the inserted magnetic nanoparticles. Benefiting from the high sensitivity of thermoacoustic emission from nanoparticles and the deep penetration capability of both magnetic field and ultrasound propagation, the proposed thermoacoustic temperature measurement system enables a high measurement accuracy of 0.5 degrees Celsius in real time. This work potentially facilitates further development of closed loop magnetic hyperthermia for practical clinical applications.

China's carbon emission trading market has been formally established, but few studies have been conducted to analyze the impact of this policy on the regional urbanization level. Therefore, this paper evaluates whether the carbon trading pilot policy can enhance the regional urbanization level in China through the difference-in-differences method and analyzes the mediating role of industrial structure upgrading in this process. The results prove that the carbon trading market policy can accelerate the transformation and upgrading of industrial structure in the region so that it promotes the development of regional urbanization. Moreover, the effects of the policy are concentratedly manifested in the eastern region of China.

There is a considerable amount of debate on the impact of capital liberalization on economic performance. Using Three-Stage Least Squares (3SLS) estimation technique introduced by Zellner and Theil (1962), we synthesize studies on the determinants of governance and capital flows. We find evidence of a revolving door relationship. Foreign aid has a negative impact on governance and, thereby reduces capital inflows since bad governance hinders capital inflows. The need to fill the gap created by private capital outflows encourages inflow of foreign aid, which in turn harms governance. Therefore, capital liberalization could grease a revolving door and undermine economic development in the aid receiving countries.

This research delves into the temporal dynamics of a nation's pursuit of a targeted GDP per capita level, employing five different survival machine learning models, remarkably Deep Learning algorithm (DeepSurv) and Survival Random Forest. This nuanced perspective moves beyond static evaluations, providing a comprehensive understanding of the developmental processes shaping economic trajectories over time. The economic implications underscore the intricate balance required between calculated risk-taking and strategic vulnerability mitigation. These findings guide policymakers in formulating resilient economic strategies for sustained development and growth amid the complexities inherent in contemporary economic landscapes.

Macrophages are a type of white blood cells that can exist in two different functional states, known as M1 and M2. M1 macrophages secrete pro-inflammatory cytokines that can promote tumor growth and metastasis, whereas M2 macrophages secrete anti-inflammatory cytokines that can inhibit tumor progression. This phenomenon, referred to as macrophage polarization, has been implicated in the development and progression of cancer. Furthermore, macrophage polarization is currently being investigated in the context of COVID-19 severity. It is believed that M1 macrophages may contribute to the excessive inflammation observed in severe COVID-19 cases, while M2 macrophages may confer protection against the disease. Hence, comprehending the role of macrophage polarization in both cancer and COVID-19 has the potential to enhance treatment strategies for both conditions.

This paper examines the link between informality and corruption, two interlinked phenomena that have negative impacts on economic development. The paper presents a neoclassical model simulation that illustrates how informality can drive corruption in the economy, emphasizing the incentives for corruption in an economy with informal and formal sectors. The model provides insights into the mechanisms that promote corruption and how policymakers can reduce it through formalisation. The paper reviews the existing literature on informality and corruption, highlighting the empirical evidence and theoretical models that support the relationship between the two. The research finds that countries with larger informal sectors tend to have higher levels of corruption. The study contributes to the ongoing debate on how to reduce corruption and promote formalisation, which are crucial for sustainable economic growth.

Population, as a fundamental element in urban development, often reflects a city's economic development pattern through its spatial distribution and dynamic changes. Studying population spatial distribution is pivotal for bolstering the economic activity capacity in urban agglomerations and guiding regional economic health. Using the Changsha-Zhuzhou-Xiangtan urban agglomeration as a case study, this paper analyzes its overall spatial structure and the spatiotemporal evolution of population at the district and county levels. This analysis utilizes population density, population redistribution index, and population geographic concentration as key indices. Additionally, a spatial econometric model is constructed to assess the impact of economic, social, and environmental factors on population spatial patterns. Findings reveal several key points: (1) Furong District serves as the primary central area, boasting a population geographic concentration of 25.1% in 2021. Tianxin District, Kaifu District, Yuhua District, Shifeng District, Yuelu District, and Hetang District constitute the secondary central areas, while Yutang District, Tianyuan District, Lusong District, Yuhu District, Wangcheng District, and Changsha County form the tertiary level areas. (2) Population density within the Changsha-Zhuzhou-Xiangtan urban agglomeration gradually decreases from Furong District outward. The first central area and sub-central areas experience increasing population density, highlighting a polarization trend in the population distribution. (3) The overall Moran's index for the spatial distribution of population in the Changsha-Zhuzhou-Xiangtan urban agglomeration is significantly positive, indicating a strong spatial autocorrelation and a deepening spatial agglomeration of population distribution. (4) Per capita disposable income, financial expenditure, and education level positively influence the geographical concentration of population in the urban agglomeration, while GDP per capita, road area per capita, and environmental quality exert a negative impact. Notably, the most influential factors shaping population spatial distribution are GDP per capita, disposable income per capita, and air quality.

Skateparks, often called 'wheel parks,' are becoming increasingly common within communities worldwide. Despite this growth in parks, estimates show that the development of parks needs to catch up to users. Using a count data travel cost model, we estimate the adult user benefits associated with the Lauridsen Skatepark in Des Moines, Iowa – the largest in the United States. We estimate adult user benefits to be $61 per user per day and roughly $488,000 annually. This work contributes to the literature by being the first study to use econometric techniques to estimate skatepark user benefits. Second, we develop a simple and easy-to-apply method to assist municipalities in determining community skatepark needs. Third, our results support the literature showing that skateboarders are increasingly diverse.

Based on provincial panel data from 1998-2018, this paper estimates research and development (R&D) factors, and a stochastic frontier analysis (SFA) model is constructed to examine the effects of R&D factors on regional total factor productivity (TFP). The results show that both R&D capital stock and R&D personnel can significantly promote regional TFP, but the productivity-enhancing effect of R&D factors is different between regions. Specifically, R&D capital and R&D personnel can promote TFP in eastern and central provinces, and the promotion effect is not significant in western provinces. In addition, compared with investment-driven regions, innovation-driven regions are more likely to enhance TFP by R&D factors.

This paper explores how digital technology reduces trade costs using bilateral trade data from RCEP member countries and a panel fixed effects model. The findings show that digital technology significantly lowers trade costs, a conclusion that holds even after accounting for lag effects and various robustness checks. The impact of digital technology on trade costs follows an inverted U-shape: the effect is most significant in the current period, especially with a one-period lag, and diminishes over time. Larger economies and higher export levels strengthen this negative impact due to their reliance on exports and continuous improvements in domestic digital technology. The study recommends investing in digital infrastructure, formulating reasonable internet access policies, supporting digital skills development, and enhancing digital connectivity to bridge the digital divide, thereby promoting trade facilitation and efficiency.

This paper uses the questionnaire data of the World Bank’s China Enterprise Survey 2012 to establish a Logit model to empirically study the relationship between knowledge sources and technological innovation in Chinese manufacturing enterprises. The results show that although internal and external knowledge has a positive effect on enterprise technological innovation in general, there are significant differences when taking the types of innovation, subject characteristic and the types of cooperation into consideration. From the current development stage of China's manufacturing enterprises, external knowledge sources, external enterprise knowledge subjects, and employee knowledge have a more positive effect on technological innovation, which also shows that the role of technical employees on technological innovation has a significant threshold effect, and only after a certain degree of accumulation can internal technical employees have a more significant positive effect on technological innovation.

Foreign direct investment (FDI) is widely viewed as a key driving force behind China’s exceptional growth performance in the last four decades. This paper investigates several questions posed by China’s success in capturing gains from FDI. What explains that success? Can other countries replicate it, or is it unique to China? What lessons are from China for other countries? China indeed has advantages in attracting FDI such as huge market and cheap labor, the well-designed policy and strategy, however, seem to play more important role in the successful story. Our empirical estimates support on four hypotheses: FDI and GDP growth in China positively interact each other; FDI is helpful to China’s technological progress, FDI promotes China’s industrial development, and FDI stimulates China’s manufactured exports.

Cancer treatment faces multiple challenges, including tumor heterogeneity, drug resistance, microenvironment influence, treatment side effects, and treatment cost. The heterogeneity of the tumor makes the effect of the same treatment vary in different patients, so the development of personalized treatment strategies is crucial. In addition, resistance of tumor cells to therapeutic drugs is a major challenge, and new strategies to overcome resistance are needed. As a cutting-edge field of science and technology, nanotechnology has brought great potential and opportunities for tumor treatment. Nanoparticle drug delivery systems improve drug efficacy and reduce side effects through precise targeted delivery and controlled release. Cell-membrane coated nanoparticles show great promise in tumor therapy. Nanoparticles coated with cell membranes have good biocompatibility, can reduce the obstacles of immune rejection and cell uptake, improve the accumulation and retention of drugs in tumor tissues, and have good drug delivery ability, drug stability and control release ability. This review discusses advances in the use of cell-membrane coated nanoparticles to target tumor drugs.