Giving full play to the interaction of multi-dimensional environmental regulation is an important method to accelerate the green transformation of manufacturing enterprises which is a significant way to achieve carbon peaking and carbon neutrality goals. Based on the theory of evolution game, a green transformation strategy evolution game model participated by the government, consumers, and manufacturing enterprises has been constructed. Stability research is conducted based on the behavioral mode of the three parties participating subjects and the paper uses MATLAB for numerical simulation to analyze the impact of environmental regulations of different dimensions on the green transformation of enterprises. The research shows that: (1) When the government adopts a single environmental regulation of carbon emission right transaction or green consumption subsidy, it will not affect the choice of green transformation strategies of the enterprise. (2) When the government adopts a single environmental regulation of environmental protection tax, it only promotes enterprises to choose green transformation strategies under limited conditions. (3) Under the multi-dimensional environmental regulations of the government, by affecting the cost and income of enterprise green technology innovation, consumers’ green consumption behavior, and the manufacturing enterprises choose green transformation as a stable strategy. Therefore, the government should give full play to the role of multi-dimensional environmental regulations in promoting consumers' green consumption and enterprises’ green technology innovation to accelerate the green transformation of manufacturing enterprises.

When human civilization is thriving to the rapid economic and social development, the deteriorating ecological environment has also pressured the society to put environmental protection issues on the agenda future development. Therefore, green innovation is not merely a requirement for a corporate’s long-term development but the basics of sustainable development of human society. As an objective indicator to measure a company's commitment to social responsibility, corporate environmental responsibility has an extremely important impact on a corporate's business philosophy and innovation strategy. However, the existing literature rarely studies between these two variables. This paper collects the data of listed companies from 2010 to 2019 and empirically tests the impact of corporate environmental responsibility on corporate green innovation. The study finds that corporate environmental responsibility can promote green innovation by reducing financing constraints, improving corporate governance and increasing government subsidies and R&D investment, and the result is still significant under a series of robustness checks. The placebo test suggests that the Jiangsu enterprise responsibility construction pilot has facilitated the development of enterprises' green innovation to a great extent. The conclusions enrich existing literature on corporate environmental responsibility and corporate green innovation, providing implications for government policy orientation, social atmosphere guidance and corporate strategic decision-making process.

This study delves into the complex relationship between China's international trade and economic growth, specifically focusing on emission intensity and its environmental ramifications within the context of energy efficiency. The primary objective is to provide a comprehensive understanding of how China's international trade dynamics influence economic growth, emphasizing emission intensity and employing a model that considers the nonlinear impact of trade on output. Through this model, structural breakpoints are identified, revealing distinct outcomes for China amidst positive and negative shocks from 1972 to 2021. The study uncovers the dual nature of the energy sector, acting both as a source of environmental degradation and a potential avenue for positive change through increased efficiency. Complex interplays among economic activities, inflation, and investment on carbon intensity are revealed. Additionally, the varying effects of export volume on carbon emissions intensity across lag thresholds underscore the significance of global trade dynamics for environmental sustainability. The study concludes by emphasizing the importance of balancing economic prosperity with environmental responsibility, advocating for carefully balanced policies that foster sustainable growth. Recommendations include considering the dual nature of the energy sector and implementing policies promoting increased efficiency. Policymakers are urged to adopt growth models prioritizing environmental responsibility, balancing economic activities, inflation, and investment to mitigate carbon intensity while acknowledging the diverse effects of global trade dynamics on environmental sustainability.

Income and population growth are key determinants of housing demand, while land use regulations are designed to affect housing supply. Previous studies of housing price determinants focus either on specific regulations in particular cities/regions, or on selective subsets of major cities and regulations. This study examines the impact of land use regulations on housing prices from 1989 to 2006 in an unusually large sample of 250 major US cities. Aside from factors that are commonly associated with housing demand (income, population growth and density), housing prices are found to be associated with local cost-increasing land use regulations (approval delays) and with statewide regulations. Since statewide regulations factor prominently into the results, specific examples of the impact of different types of land use regulations are provided for 5 cities in the state of Washington. The estimated increase in housing prices associated with regulations is, on average (over 250 cities), substantially larger than the effects of income and population growth. While the estimated dollar costs associated with regulations may be sizable at times, the results are remarkably consistent with previous studies that were based on smaller cross sections.

Cryptocurrencies have gained popularity over the past five to six years. Most recently, events like the FTX bankruptcy fueled the interest in regulation. Moreover, it is possible that the FTX event disrupting the cryptocurrency market was a factor in Silicon Valley Bank's failure. While several countries consider regulation, from soft regulation, like Japan, to more rigid standards, like the total ban in China, we study the effect of other news or events on cryptocurrency prices. This paper looks at historical closing prices for Bitcoin, the largest of the cryptocurrencies, and how prices react to various events. Then we focus on modeling the time series considering an 'event,' China's ban on cryptocurrency exchanges, using intervention analysis. We find that intervention analysis provides a reliable approach to quantifying the impact regulation may have on cryptocurrency pricing.

Investment funds are increasingly focusing on ESG issues, seeking to contribute to improving environmental, social, and governance concerns. ESG-focused investing involves promoting good ESG performance and may result in a decrease in expected financial returns. This may lead to a conflict between solely profit-focused shareholders and ESG-focused investors, who may respond accordingly. As such, a firm's ESG commitment may trigger several events that can affect the stock price. A firm's ESG commitment may increase its stock price; however, the end of such commitment may also positively affect the stock price. Hedge funds may consider this in their activism which may reshape the way hedge funds target firms and influence their actions accordingly.

Green innovation, as a sustainable development approach, can synergistically promote high-quality economic and social development. We select China's A-share-listed manufacturing corporations from 2011 to 2021 as the research sample to empirically study the impact of executive academic experience on green innovation in manufacturing corporations. Further, we test the relationship between executive academic experience and green innovation in manufacturing corporations under the mediating role of corporate social responsibility and the moderating role of heterogeneous environmental regulations. The study shows that (1) executive academic experience helps to promote green innovation in manufacturing corporations; (2) executive academic experience is conducive to promoting the fulfillment of social responsibility by manufacturing corporations; (3) corporate social responsibility plays a mediating role between executive academic experience and green innovation in manufacturing corporations; (4) environmental regulation positively moderates the relationship between executive academic experience and green innovation in manufacturing corporations, and both formal environmental regulation and informal environmental regulation positively moderated the promotion of green innovation in manufacturing corporations by executive academic experience.

The implementation of environmental protection strategy necessarily requires mapping the amount of capital stock of environmental infrastructure. Through the Weibull distribution function and hyperbolic age-decreasing efficiency model, the provincial environmental infrastructure capital stock in China from 1980 to 2018 is measured cautiously, and its spatial dynamics with the generated pollutants is analyzed using the center of gravity method. It is found that: the spatial distribution of environmental infrastructure capital stock is uneven, and the unevenness in the east-west direction is greater than that in the north-south direction, but the unevenness in the east-west direction is narrowing while the north-south direction is widening; the spatial and temporal distribution of environmental infrastructure capital and environmental pollution vary greatly, and the spatial management of environmental pollution is less accurate.

Environmental degradation is becoming a fundamental issue as it is directly associated with human lives and environmental sustainability. This research particularly highlights the significance of green transportation taxes in achieving environmental sustainability due to limited available literature considering the environmental sustainability and green transportation taxes nexus. By employing the newly developed QARDL approach, this study is unfolding the linkages of green transportation taxes on transport-based CO2 emissions for Chinese economy spanning 1992 to 2020. The results infer that green transportation taxes to enhance environmental sustainability in the long-run for the highest quantiles, i.e., 0.70 to 0.95. Though, green transportation taxes enhance environmental sustainability in all quantiles in the short-run. Based on these results, the study suggests that the Chinese government and policymakers should increase green transportation taxes that help in combating CO2 emissions, which ultimately enhances environmental sustainability.

The sensitive nature of interest rate has spurred empirical interests on the factors that determine it. This paper examined the joint impact of exchange rate and foreign direct investment inflows on interest rate in Nigeria over the period from 1981-2022. The study made use of the auto regressive distributed lag (ARDL) bounds test and results of findings reveal that in both the short-run and the long-run the impact of the interaction between FDI inflows and exchange rate on real interest rate was negative and significant. Also, while credit to the private sector was found to have significant positive impact on real interest rate in both the time horizons, the impact of consumer price index was negative only in the short. Oil revenue was found to impact positively on real interest rate only in the long-run, but the impact of broad money supply was negative and significant in both the short-run and the long-run. The study suggests that policies to regulate domestic interest rate should focus on joint regulation of both exchange rate and FDI inflows and this requires a synergy between monetary and fiscal policies.

The digital transformation provides an opportunity for the development of a green and low-carbon economy. This study used panel data collected from 30 Chinese provinces between 2011 and 2018, and assessed the impact of digitization (Dig) on environmental efficiency (EE). Quantile regression is employed to scrutinize the evolution of the marginal effect. From the perspectives of population and institutional factors, this study empirically investigates nonlinear relationships and potential mechanisms using Hansen threshold and mediation models. The findings reveal several key insights. Overall, levels of digitization and environmental efficiency (EE) are increasing with regional dispersion expansion, indicating a “polarization” characteristic. The impact of digitization on EE exhibits noticeable stage and regional heterogeneity. Analysis of population factors reveals that population structure, population size, and human capital trigger a sharp “marginal increase” of positive effects with single thresholds of 0.8155, 7.2284, and 11.0497, respectively. Analysis of institutional factors highlights the significance of fiscal policy quality (tax proportion), education expenditure, and tax system structure as important intermediaries. Finally, this paper presents corresponding policy implications.

The impact of international tourism on emerging markets has been overwhelmingly beneficial. Despite the obvious benefits of tourism, it comes at a high price for the environment in the form of pollution. Brazil's annual tourist influx has the potential to boost economic development and damage the country's ecosystems. The objective of this investigation is to analyze, using time series data ranging from 1990 to 2019, the effects of tourism and economic growth (GDP) on carbon dioxide (CO₂) emissions in Brazil. The stationarity of the data was examined by employing unit root tests, and an autoregressive distributed lag (ARDL) technique was used to investigate the link between the factors, taking both the long- and the short-run into consideration. This research shows that there are long-term and short-term ties between Brazil's tourism industry, GDP, and CO₂ emissions. Yet, both tourism and economic expansion have had serious negative effects on Brazil's ecology. These results indicate that in order to maintain environmental quality in Brazil, policymakers need to pursue more eco-friendly economic expansion as well as environmentally conscious tourist regulations.

This study delves into the intricate interconnections among the financial sector, macroeconomic dynamics, and the advancement of sustainable energy production in South Asia. Utilizing data from 1987 to 2022 in Bangladesh, India, Pakistan, and Sri Lanka, the research employs the Structural Vector Autoregressive (SVAR) method to analyze financial market responses. The findings reveal nuanced insights into the complex relationship between economic and environmental factors, fostering a comprehensive understanding of the region's intricate nexus between financial markets and sustainable energy initiatives. In the Economic Growth model, the negative coefficient for CO2 emissions underscores environmental concerns, indicating an inverse relationship with economic growth. Conversely, positive coefficients for non-fossil energy production, Gross Fixed Capital Formation, stock exchange value, and domestic credit emphasize their positive impact on economic growth. A positive GDP coefficient in the CO2 emission model signifies heightened carbon emissions with economic growth, while a negative coefficient for non-fossil energy production suggests potential environmental benefits. The nearly unitary positive coefficient for Gross Fixed Capital Formation highlights its significant role in driving carbon emissions. The Non-Fossil Energy Production model reveals an inverse relationship between GDP and clean energy, suggesting a potential reliance on fossil fuels during economic growth. Positive coefficients for CO2 emissions, Gross Fixed Capital Formation, stock exchange value, and domestic credit highlight factors influencing non-fossil energy production. Long-run stable coefficients affirm variable significance, while a negative error correction term suggests convergence in developing countries. These models offer nuanced insights into the intricate relationships among economic, environmental, and energy variables, guiding sustainable development policies in South Asia.

The present paper empirically examines the validity of the environmental Kuznets curve (EKC) hypothesis, which posits an inverted U-shaped relationship between CO2 emissions and economic growth, in Egypt, India, Mexico, Pakistan, Thailand, and Turkey for the period 1970-2020. The EKC validity is highly debated due to varying results across countries. This study is significant to addresses this controversy by estimating the EKC's robustness while considering the influence of financial development, globalization, and government expenditure. We employ two cointegration techniques, the autoregressive distributed lag (ARDL) and vector error correction model (VECM), also considering potential structural breaks in the data. Out key findings indicate that the EKC hypothesis is supported in India, Pakistan, and Turkey, with carbon emissions eventually declining after reaching a peak. The hypothesis is not supported in Egypt and Thailand, where emissions rise monotonically with economic growth. In Mexico, the results are mixed, with ARDL suggesting a U-shaped relationship and VECM supporting the EKC. From our empirical analysis of the EKC hypothesis, we derive the following policy implications: 1) countries should adopt comprehensive policy strategies that integrate these goals and fully consider the long-term environmental and societal impacts of their decisions; 2) countries should invest heavily in research and development to accelerate the creation of new technologies that can effectively reduce carbon emissions; and 3) countries must actively raise awareness about the environmental repercussions of economic growth.

Green innovation, driven by China's new development concept, plays a crucial role in high-quality economic development. In line with the green development trend, businesses increasingly prioritize whether their corporate environmental responsibilities (CER) can effectively enhance corporate green innovation (CGI) levels. This paper examines the influence and mechanism of CER on CGI using a dynamic perspective, drawing from 1,640 manually-collected panel data of Shanghai and Shenzhen A-share listed companies between 2010 and 2017. The primary findings indicate that the impact of CER on CGI possesses phase-specific characteristics and a dual effect of "crowding in" and "crowding out." The current phase of CER negatively affects green innovation, while the lag phase has a positive effect. CER's impact on various CGI types is heterogeneous: specifically, it follows an "inverted-N" trajectory (inhibition-promotion-inhibition) for "strategic green innovation" and has a promotional effect on "substantive green innovation," which is stronger and has a longer time lag. The mechanism analysis reveals that financing constraints play a critical mediating role. A heterogeneity analysis based on multiple dimensions (ownership, industry, and location) suggests that CER has a more significant driving force for CGI among state-owned firms, high-polluting industries, and enterprises in inland areas. Finally, the paper presents corresponding suggestions for government and corporate entities.

The latent transforming growth factor-beta (TGF-β) binding protein 1 (LTBP1) has been implicated in various cellular processes, but its role in triple-negative breast cancer (TNBC) remains unclear. In this study, we investigated the impact of LTBP1 on TNBC progression and its underlying mechanisms. Analysis of online datasets revealed elevated LTBP1 mRNA expression in breast cancer tissues compared to normal adjacent tissues. Kaplan-Meier Plotter analysis indicated that high LTBP1 expression was negatively correlated with relapse-free survival (RFS), distant-metastasis free survival (DMFS), and overall survival (OS) of breast cancer patients. Additionally, LTBP1 mRNA levels were associated with chemotherapy resistance. Functional assays in TNBC cells demonstrated that LTBP1 knockdown suppressed cell proliferation, induced apoptosis, and attenuated migration and invasion. In vivo studies confirmed that LTBP1 knockdown inhibited tumor growth in a xenograft mouse model. Mechanistically, LTBP1 positively correlated with genes involved in signaling regulation and organelle organization, with significant associations to GTPase binding and the RhoA/ROCK pathway. LTBP1 knockdown reduced RhoA activity and phosphorylation of Myosin Light Chain 2 (MLC2), suggesting inhibition of the RhoA/ROCK signaling pathway. Moreover, activation of the RhoA/ROCK pathway partially rescued the effects of LTBP1 knockdown on TNBC cell proliferation, apoptosis, migration, and invasion. In conclusion, our findings suggest that LTBP1 promotes TNBC progression through activation of the RhoA/ROCK signaling pathway, highlighting its potential as a therapeutic target for TNBC.

The digital economy based on digital technology is an important force for high-quality economic growth and industrial transformation, and has great potential for value creation. Based on the data of 30 provinces in China from 2007 to 2017, this paper uses entropy method to calculate the industrial green transformation (IGT), and empirically analyzes the impact of Digital economy on IGT. The DE can significantly reduce IGT of local and neighboring areas after excluding the influence of macro system factors and replacing the spatial weight matrix. The DE can indirectly reduce the IGT by accelerating the accumulation of human capital, and green technology innovation. The impact of digital economy on IGT is a non-linear relationship. With the further improvement of environmental regulation, financial development and intellectual property protection, the role of digital economy in IGT is more obvious. To this end, it is necessary to speed up the construction and improvement of digital infrastructure, build an integrated layout of "digital infrastructure", give full play to the radiating role of the digital economy, and implement differentiated development paths based on regional comparative advantages.

With the development of information technology and its application in environmental governance, the role of the internet in improving energy efficiency and reducing energy-saving potential (ESP) has attracted more attention. In this study, the slack-based model (SBM) and the unexpected model, along with the entropy method, were applied to measure China's energy-saving potential and internet development. Further, we empirically analyzed the direct effect, mediating effect, threshold effect, and regional heterogeneity of the internet on ESP. Our conclusion shows that there is a significant spatial correlation between internet penetration and ESP. Internet penetration has become an important tool for reducing ESP, but this effect shows regional heterogeneity. Human capital accumulation, financial development, and industrial upgrading are important influencing mechanisms, but indirect effects are weaker than direct effects. The impact of internet penetration on ESP is non-linear, and for improving human capital accumulation, financial development, and industrial upgrading, the role of internet popularization in energy conservation is more obvious.

With the continuous advancement of technological revolution and industrial transformation, digital finance supported by big data and artificial intelligence has become an important engine for promoting carbon neutrality. We measured the industrial structure transformation index (ISU) of 30 provinces in China, and discussed the spatial spillover effect and transmission mechanism between digital finance and ISU using the spatial Durbin model. The research results demonstrate that the digital finance development can significantly improve the local ISU. Interestingly, the impact of digital finance on the ISU of adjacent areas has a significantly negative spatial spillover effect, which still exists under the different spatial weight matrix. Digital finance can improve ISU by improving green technology innovation, upgrading industrial structure, and alleviating capital allocation. We also found that the higher degree of marketization and environmental regulation can increase the positive influences of digital finance on ISU. This research proves the effectiveness of the digital finance in improving energy efficiency, and it encourages policymakers around the world to rely on digital finance to promote ecological governance and achieve high-quality economic development.

Nanomaterials have shown great potential in anti-tumor applications and are currently the focus of research. This review article aims to provide a comprehensive overview of the challenges encountered in oncology treatment and how nanomaterials are being utilized to overcome these obstacles. The authors discuss the limitations of conventional treatments, including limited efficacy, side effects, and toxicity issues. They highlight the importance of early tumour diagnosis and personalized treatment plans, as well as the need for innovative therapeutic approaches such as targeted therapy, immunotherapy, and gene therapy. The article primarily focuses on how nanomaterials can be engineered to achieve specific recognition and aggregation within tumour tissues through surface modifications involving targeting molecules such as antibodies, peptides, and receptor ligands. This surface modification technique facilitates improved targeting in the targeting of photodynamic therapy, while minimizing harm to normal tissues. The authors also discuss the potential and future prospects of nanomaterials in tumour therapy, including breakthroughs in their application, biosafety concerns, biocompatibility issues, preparation processes, clinical translation challenges, interdisciplinary cooperation, international exchange, relevant regulations and ethical guidelines. Overall, this review highlights the substantial potential of nanomaterials in oncology treatment, emphasizing the need for careful consideration of safety concerns to ensure their safe and effective application. The authors conclude that strengthening interdisciplinary cooperation and international exchange will contribute to the healthy development of nanomaterials in oncology treatment.